The Belgium midfielder was withdrawn after less than an hour in City's 9-0 rout of the League One side, which all but secured their spot in the EFL Cup final.
Guardiola said: 'A month ago I read about Ruben Neves - £100m! That is not going to happen.
"We have a limit and cannot spend more so that's why we need to be careful with the players and try next season to see what we can do to improve".
Neves, whose Wolves side visit the Etihad on Monday, tends to play as one of two holding midfielders, whereas Fernandinho performs that role on his own in the City line-up.
Shutdown restricting visits, cleaning at national parks
And for those planning a visit there, Lost Horse Mine Road and Rattlesnake Canyon are also closed effective immediately. Many National Parks have resorted to partial road closures to help curtail the number of users entering remote areas.
"We realised when we played the EFL (English Football League) Cup and the first away game how complicated it would be", said Guardiola of the threat posed by high-flyers Wolves.
"But I'm not talking about the case of the Ajax player [Frenkie De Jong] because he is an Ajax player. I don't talk about players not here, never did and never will".
The 33-year-old Brazilian was badly missed as City suffered costly back-to-back defeats to Crystal Palace and Leicester over Christmas.
"It's not easy to find the specific quality of the players", said Guardiola. He knows the Premier League, after three years together here, he knows everything and that's so important.
Tottenham's struggles in the midfield department have been well documented this season, with a host of key midfielders missing out due to frequent injuries over the course of the season. "He'll be 34 and he can not play every few days".
But with City still fighting for silverware on four fronts, the Catalan is happy to rely on John Stones and Ilkay Gundogan until the end of the season.
"Sergio after Liverpool was sick", Guardiola added. He had more space than usual but he was so clever. In fact, he has averaged 80 passes this season with an incredible accuracy of 92%.
"There are many clubs in the world, many holding midfielders in the world, and a lot of them can play here. He's a fantastic player".
"I don't know what happened, he didn't speak to me, so I don't know what happened", said the City boss.
Kevin Spacey in Nantucket court over alleged sex assault
On Monday, the judge granted a defense request to preserve cellphone evidence and set a preliminary hearing date for March 4. One former production assistant told CNN that Spacey sexually assaulted him during one of the show's early seasons.
Didn’t know about allegations Manafort shared polling
Prosecutors say Manafort acknowledged the meeting only after being told that they were in the same city on the same day. CNN reporters had first observed Fabrizio at the special counsel's office in Februrary 2018, according to the report.
Canadians held in China since arrest of Huawei executive
December 29: A Chinese court orders a retrial for Schellenberg, raising the possibility of a harsher sentence, including death. There were reports that has confirmed the detention of Spavor and Kovrig were tied to the arrest of Huawei's CFO.
Golden Globe Awards 2019
The inclusion of minorities among this year's Golden Globes nominees and winners still marks a step in the right direction. Hosting the gala were comedian Andy Samberg and actress Sandra Oh .
We now have the official release date for Stranger Things 3
The clip then becomes distorted, with the television going black and showing an announcement, "One summer can change everything". Netflix followed up by tweeting a poster for Stranger Things 3 right after it debuted the release date trailer .