South Carolina's Emergency Management Division said residents should begin preparing their homes and property for the storm.
On its current path, winds from the hurricane, which are travelling at 15mph from the centre, will move over the southwestern Atlantic Ocean between Bermuda and the Bahamas on Tuesday and Wednesday.
The Miami-based center said that it was still too early to predict the hurricane's exact path but that a huge coastal area from SC to the mid-Atlantic region should prepare for a major strike late in the week.
Another tropical storm has now developed in the Atlantic and could possibly hit the British Virgin Islands as a hurricane in the next few days.
Isaac will be near the Lesser Antilles later this week and could bring impacts to parts of the Caribbean Islands during this time frame.
IPhone 9 could cost more than iPhone 8
"They expect Apple to announce three new phones, two with screens larger than 6" and one just below, at an event next week . The CPU is expected to have 8 cores and at least 4GB of RAM with up to 512GB of storage rounding out the specs.
Xi announces $60bn financing for Africa
Xi told him on Sunday that "foreign forces" should not interfere in Sudan's internal affairs, China's Foreign Ministry said. At the last three-yearly gathering in Johannesburg in 2015, Xi announced $60 billion of assistance and loans for Africa.
Facebook, Twitter defend efforts to stop election meddling
Chief election commissioner O P Rawat told TOI that "EC's interactions with the three social media companies are complete". Many senators expressed anger at Google, which was represented in the hearing room by an empty chair next to Sandberg.
California Lawmakers Pass Net Neutrality Bill
California lawmakers have voted to make net neutrality state law, becoming the latest of several states to approve such measures. In addition, it would prohibit internet providers from collecting fees from apps and sites in order for them to reach users.
Keys to face Osaka in US Open semis; Nishikori beats Cilic
Osaka was an easy victor in her quarterfinal, eliminating unseeded Lesia Tsurenko of Ukraine 6-1, 6-1 in all of 57 minutes. In the match before Nishikori's, Naomi Osaka moved into her first Grand Slam semifinal by routing Lesia Tsurenko 6-1, 6-1.
McCain's final statement: Americans have 'more in common'
McCain served as a naval pilot in the Vietnam War, spending five years as a prisoner of war after his plane was shot down in 1967. The American flag that flies above the White House was at full staff on Monday-shortly after it was lowered in honor of Sen.
Serena, Venus to meet in third round of US Open
Venus, the 2000 and 2001 champion, made the third round for the 17th time with a 6-4, 7-5 victory over Camila Giorgi of Italy. The last time they played each other though, in the third round in Indian Wells 2018, Venus won the match in straight sets.